Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---CTYSVYDSIGKMVVEDKDLPTNRRDYYTIGKKKYTFYFKENCDFDYSKPPLPRCWHVSGI------------------------------------------------------------------------------------------------------------------------------------------- 1UUN Chain:A ((1-184)) GLDNELSLVDG------QDRTLTVQQWDTFLNGV------------FPLDRNRLTREWFHSGRAKYIVAGPGADEFEGTLELGYQIGFPWSLGVGINFSYTTPNILIDDGDITRPPFGLNSVITPNLFPGVSISADLGNGPGIQEVATFSVDVSGAEGGVAVSNAHGTVTGAAGGVLLRPFARLIASTGDSVTTYGEPWNMN

General information: TITO was launched using: RESULT: Template: 1UUN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 66 5433 82.32 129.36 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain A : 0.50 3D Compatibility (PKB) : 82.32 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.50 QMean score : 0.066

(partial model without unconserved sides chains): PDB file : Tito_1UUN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1uun-query.scw PDB file : Tito_Scwrl_1UUN.pdb: