Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGRLCVSDSEALVL-LQSLPHVPQPVHIRRSSQGGE--HLVWTVNDALV-LRIPADQSNAEPLLRERRL-LDLLRRNDKIAPV-VPPCIDVGVWNPHGWQYALYH-KATGVSVESDPQAVT-NATEDDLVELL-VGLRGV-GVGDALGVGVPEGDEVDFEKLRGNARAALDVLQKSQQLMELGEVVS-LEK-LDAPWFVRLGGSMRRVLSHADLKGEHV-FLDAAGRVTGVIDWSDAQVGCP----------------------SVEVAGLAVAVGARMAARVAKRAGYEADIVCKGVIMAR-CNGVVCLEAI-LRGADDSPECLVRRQLGRAFEE-LD-A--------- 3DXP Chain:A ((20-359)) ----RFDTEALEAWMRQHVEGFAGPLSVEQFKGQSNPTFKLVTPGQTYVMRA------KPGAIEREYRVMDALAGTDVPV-AKMYALCEDESVIGR-----AFYIMEFVSGRVLWDQSLPGMSPAERTAIYDEMNRVIAAMHTVDYQAIGLG-----DYGKPGNYFQRQIERWTKQYKLSETESIPAMDSLMDWLPQHIPQEDADLTSIVHGDYRLDNLMFHPTEPRVLAVLDWELSTLGHPMGDFGYHCMSWHIAPGQFRGIAGLDHAALGIPDEASYRKLYEQRTGRPITGDWNFYLAFSMFRIAGILQGIMKRVVDGTASSAQALDAGKRARPMAEMGWEYAKKAKQ

General information: TITO was launched using: RESULT: Template: 3DXP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1249 -1135 -0.91 -4.04 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -0.91 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.291

(partial model without unconserved sides chains): PDB file : Tito_3DXP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxp-query.scw PDB file : Tito_Scwrl_3DXP.pdb: