Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTPDRPEAEIEAMSALFARHLPGLAARSVTRLGEGMDHVAYEADGGLILRMSKEPDPARRADRIRREAALLALVAEISPLPVPRVILS-----DPDAGVLGYVKLPG-----RPLAERPVAEPGRLAPALGEFLTRLHLAPPERFSALAAPDTQPLTAWLAEAERHHRAVAAHLPAAARRRIEAFLGGAPPAEPRALAF-C--HNDLGAEHVL--AEGGTVTGVIDWSDAEIADPAYDLGLLYRD---LGPEVTASILAHYAAPWDDAAGRRAVFYARCALLEDLAYGLRTGPRRYAEAALAHLDRTFSAWG 4N57 Chain:A ((25-315)) -TFDQVEKAIEQL-------YPDFTINTIQISGKGNDCIAYEINRDFIFKF---PKHSRGSTNLFNEVNILKRIHNKLPLPIPEVVFTGMPSETYQMSFAGFTKIKGVPLTPLLLNNLPKQSQNQAAKDLARFLSELHSINISGFKSNLVLDFREKIN--EDNKKIKKLLSRELKGPQMKKVDDFYRDILENEIYFKYYPCLIHNDFSSDHILFDTEKNTICGIIDFGDAAISDPDNDFISLMEDDEEYGMEFVSKILNHYKHKDIPTVLEKYRMKEKYWSFEKIIYGKEYGYMDWYEEGLNEI--------

General information: TITO was launched using: RESULT: Template: 4N57.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1204 -17381 -14.44 -63.66 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -14.44 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.471

(partial model without unconserved sides chains): PDB file : Tito_4N57.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4n57-query.scw PDB file : Tito_Scwrl_4N57.pdb: