Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGRLCVSDSEALVLLQSLPHVPQPVHIRRSSQGGEHLVWTVNDALVLRIPADQSNAEPLLRERRLLDLLRRNDKIAPVVPPCIDVGVWNPHGWQYALYHKATGVSVESDPQAVTNATEDDLVELLVGLRGVGVGDALGVGVPEGDEV--DFEKLRGNARAALDV-LQKSQQLMELGEVVSL-EKLDAPWFVRLGGSMRRVLSHADLKGEHVFLDAAGRVTGVIDWSDAQVGCPSVEVAGLAVAVGARMAARVAKRAGYEADIVCKGVIMARCNGVVCLEAILRGADDSPECLVRRQLGRAFEELDA 3W0Q Chain:A ((46-232)) --------------------------------------------YVLRV---NSCADGFYKDRYVY---RHFASAALPIPEVLDIGEFS-ESLTYCISRRAQGVTLQDLPETELPAVLQPVAEVMDAIAAADLSQTSGFG-PFGPQGIGQYTTWRDFICAIADPHVYHWQTVMDDTVSASVAQALDELMLWAEDCPEVRHLVHADF-GSNAVLTDNGRITAVIDWSEAMFGDPLYEVANI------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3W0Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 755 -37108 -49.15 -202.78 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -49.15 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.231

(partial model without unconserved sides chains): PDB file : Tito_3W0Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3w0q-query.scw PDB file : Tito_Scwrl_3W0Q.pdb: