Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSHIQRETSCSRPRLNSNLDADLYGYRWARDNVGQSGATIYRLYGKPNAPELFLKHG----KGSVANDVTDEMVRLNWLTAFMPLPTIKHFIRTPDDAW--LLTTAIPGKTAFQVLEEYPD--SGENIVDALAVFLRRLHSIPVCNCPFNSDRVFRLAQAQSRMNNGLVDASDFDDERNGWPVEQVWKEMHKLLPF------SPDSVVTHGDFSLDNLIFDEGKLIGCIDVGRVGIADRYQDLAILWNCLGEFSPSLQ--KRLFQKYGIDNPDMNKLQFHLMLDEFF 1J7U Chain:A ((2-264)) ----------AKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENEN--LYLKMTDSRYKGTTY-DVEREKDMMLWLEGKLPVPKVLHFERH--DGWSNLLMSEADGVLCS---EEYEDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADV-----DCENWEEDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKWYDIAFCVRSIREDIGEEQYVELFFDLLGI-KPDWEKIKYYILLDELF

General information: TITO was launched using: RESULT: Template: 1J7U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1094 12943 11.83 52.40 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : 11.83 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.448

(partial model without unconserved sides chains): PDB file : Tito_1J7U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1j7u-query.scw PDB file : Tito_Scwrl_1J7U.pdb: