Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTASVEVPQYVAEETTARWPNVGPQWVSEAPGELRQLCEQYGAIPETVLPARYGLVVAVQAKDRELIMKGSPDP-----DGPNQVKVMSALADLQVGPTILESFSTDTGFWTIMTRIKPGE-PLRNLGASLAPPDKLATILRPLVNQPSPSSTL-P---YIGDWLRDRLEDDALSDLAPGRTVASETERSEALSVLSELTDAG-AQGLCHGDTSPGNILTGENGKLYLIDPR-GMRGEAAYDVAVLGLKSA-MTVSPETRVSDLAKAVGVDVGRAERWAAIALAARV 4R7B Chain:A ((46-252)) -------------------------------------------------GGMTNQNYLAKTTNKQYIVKFFGKGTEKLINRQDEKYNLELLKDLGL-DVKNYLF-DIEAG-IKVNEYIESAITLDSTS-IKTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEE------QIP--YANYESVRNAVFSLEKRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTSQEEETFLSHYESDQ-------------------

General information: TITO was launched using: RESULT: Template: 4R7B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 740 31484 42.55 162.29 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 42.55 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.270

(partial model without unconserved sides chains): PDB file : Tito_4R7B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4r7b-query.scw PDB file : Tito_Scwrl_4R7B.pdb: