Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKSKELEIVKKLTNVADENNIVLNEDGWTSRVYIVNKGEIV-LKFLKNKQYREEFEHEINILKLIKDH-KFNVNIPLISSSEEDNTYIVLN--GLMGKSMSAEIVDALTKEEKRKIGTQIGLFLKKLHTVAYQGKSP---NNESEIFEWFQKSFNRRKRTLKKHFNENELVAIE-DLVTTLPQRSQKLGIVQ---VFCHGDLGYNNILLT-DSLEVGVIDFGDAGYNDQSYDFVGLEDD-------DMLDAVILAYDGDEILKAK--VEIRRQLLPLMEMLFLIDKKDKEGVQQCVKRVRINLKMHEIYNG 6CGD Chain:A ((37-298)) ---------------------------GYDSVAYLVNNEYIFKTKFSTNK--KKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEY---------ILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEI------------

General information: TITO was launched using: RESULT: Template: 6CGD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1044 2689 2.58 11.16 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : 2.58 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.420

(partial model without unconserved sides chains): PDB file : Tito_6CGD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-6cgd-query.scw PDB file : Tito_Scwrl_6CGD.pdb: