Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVELTDPDLERLRRRLAPAHIEDLRPLTGGASSLTYAGQRLGDRVVVKMAPPGIQPTRNRDVLRQCRIIKALRATPVPVPDVLWADAGDPPEIPPLFVMSWIDGSSLEPLFDLDCACESEDIVAERFRSAAATMAQLHRIQPAA-IGLGSEPI------VGAEAEIDRWCRALE-TVDPTLAAGWIDLGKALRAAAPPPLPPAVVHGDFRLGNLRAVDGRITGVLDWEIWSVGDPRVDVGWFLINCDRQTYQRATPYAGATPSPAELVSIYCAAAGYRLPDLAWFQALACFKSAATWSLIVKHNRRRHRPDANVEAMAQVLPHLLSRACILLD 3W0Q Chain:A ((8-229)) -----ATSVEKFLIE-KFGSVSDLMQLSEGEESRAFSFDVGGRGYVLRVNSCADGFYKDRYVYRH------FASAALPIPEVL--DIGEFSESLTYCISRRAQGVTLQDLPETELPAVLQPVAEVMDAIAAADLSQTSGFGPFGPQGIGQYTTWRDFICAIADPHVYHWQTVMDDTVSASVAQA---LDELMLWAEDCPEVRHLVHADFGSNAVLTDNGRITAVIDWSEAMFGDPLYEV----------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3W0Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 845 -57201 -67.69 -267.29 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -67.69 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.208

(partial model without unconserved sides chains): PDB file : Tito_3W0Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3w0q-query.scw PDB file : Tito_Scwrl_3W0Q.pdb: