Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTRPPTPTADTVRRLVRTLLKDGAADASGPEVRPAAPGADPVTWLVGGRHVLRLARDRDAAARQRRELRLRDLVRTHVPVAVP---VSVAQGEWAPGLAYTLDTRV-PGASGAEHDV---SAVGEADLAGLLTGLREVPARQAETLGVPRAAPRSLEALRAAAEPAAERLAGADEFDAARLRQLTRAAAVQLAAQSAPP---VLVHHALTGGHLVVSADGRVRAVLGWAGTVLGDPAEDIAGLALAVGSPAAVRAATLAGYGARPCLRGLWLARCDAVLQLAARLDGTGTAPLPRLRTRLRHAWEAILLERVTELRAEAGEDGERRA 5IGT Chain:A ((46-240)) ----------------------------------------------GRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQA---RQKVADDVDRVRREFVVNDKRLHRWQR----WLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVFG-------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5IGT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 682 -27982 -41.03 -151.25 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -41.03 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.305

(partial model without unconserved sides chains): PDB file : Tito_5IGT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5igt-query.scw PDB file : Tito_Scwrl_5IGT.pdb: