Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIDTDSLKNARFYATKTEPITDVDIVAEAPLERPELIKGKDAPGILTFARVHREGGSDLYQLVVDKQGRDILGEEETARAAGKQLSNGYAVGSGVLHKLTDPALPPVETVRAVGEQSNTSWIYNDRVIVKYFRRLTPTPNPEIELLEELTAAGCTHSAPLRGWTSVDIEGHTYVTAMLQDLVPG-TDGYDYVTGT-----------------PDAFDATALGEAIRDVHTVLASTCETGTLAPGALATNLDRRLTGLVGRAPQLKEYEEKIRALYSTLAETSVPTQRIHGDLHLGQTLVDGDSWALIDFEGEPAASLEERRRPDSPLRDVAGMIRSFGYAAAASG----------------QDQSWADARTAELIAGYGEA-------DEAILRAYIADKCAYEVVYELENRPHMVHVPLDALASLV 5JY7 Chain:O ((198-439)) --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ANSAEGWDMATTSTRDLFAEGDLYAEEVGGDFAGEAYRLGEAVASVHACLAHELGTE-EVPF-PADVMAQRLAAAVDAVPELREHVPQIEERYHKLADTTMTVQRVHGDLHLGQVLRTPKGWLLIDFEGEP---LDERRRPDTPVRDVAGILRSFEYAAHQRLVDQAGDDDDRARQLAARAREWVTRNCASFCDGYAAEAGTDPRDSADLLAAYELDKAVYEAAYEARHRPSWLPIPLGSIARL-

General information: TITO was launched using: RESULT: Template: 5JY7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain O - contact count / total energy / energy per contact / energy per residue : 747 11719 15.69 59.19 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain O : 0.66 3D Compatibility (PKB) : 15.69 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.253

(partial model without unconserved sides chains): PDB file : Tito_5JY7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5jy7-query.scw PDB file : Tito_Scwrl_5JY7.pdb: