Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTASVEVPQYVAEETTARWPNVGPQWVSEAPG--ELRQLCEQYGAIPETVLPARYGLVVAVQAK---------DRELIMKGSPD--PDGPNQVK-------VMSALADLQVGPTILESFSTDTGFWTI-----MTRIKPGEPLRNL---GASLAPPDKLATILRPLVNQPSPSSTLPYIGDWLRDRLE--DDALSDLAPGRTVASETE-RSEALSVLSELTDAGAQGLCHGDTSPGNILTGENGKLYLID-----PRGMRGE----AAYDVAVLGLKSAMTVSPETRVSDLAKAVGVDVGRAERWAAIALAARV 4WMY Chain:A ((24-306)) CSSSPSLPRSCKEIKDECPSAFDGLYFLRTENGVIYQTFCDM------TSGGGGWTLVASVHENDMRGKCTVGDRWSSQQGSKAVYPEGDGNWANYNTFGSAEAATSDDYKNPGYYDIQAKDLGIWHVPNKSPMQHWRNSSLLRYRTDTGFLQTLGHNLFGIYQKYPVKYGEGKCWTDNGPVIPVVYDFGDAQKTASYYSPYGQREFTAGFVQFRVFN--NERAANALCAG-----MRVTGCNTEHHCIGGGGYFPEASPQQCGDFSGFDWSGYGTHVGYSSSREIT-----------------EAAVLLFYR-

General information: TITO was launched using: RESULT: Template: 4WMY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1363 23477 17.22 96.61 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 17.22 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.212

(partial model without unconserved sides chains): PDB file : Tito_4WMY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4wmy-query.scw PDB file : Tito_Scwrl_4WMY.pdb: