Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MADRFIGSAVAVPASLDWLRATETGRIWLDKLPVLLETACEHFGLSEIGSPFSGGNVSLVVPARHDGEDVVLKLQFPD-HECRHEAEALWRWNGKGA-VRLLKHAPELGALLLERCRPGQ-FLADDTE---TDRIGVVAGLLRLLTIPAGD-PFT-RLNDEAARWRDSLDHNWMAAGKPCEQYLVDAARKALQDLCLEKEAEEVLLHQDLHGHNILSSERDTWLAIDPK-PLAGDPAFALSPIVRSFEFGHSKAEARYRLDRLSEELE--LDRERARYWTIGQTMAWAFSSSYAERHFETVRWLLAEN 3DXQ Chain:A ((25-263)) ---------------------------------------------------RLGGLTNLVFRA----GDLCLRIPGK-YINRANEAVAAREAAKAGVSPEVLHVDPATGVMVTRYI-AGAQTMSPEKFKTRPGSPARAGEAFRKLHGSGAVFPFRFELFAMIDDYLKVLS--NVTL-PAGYHDVVREAGGVRSALAA-HPLPLAACHCDPLCENFLDTG-ERMWIVDWEYSGMNDPLWDLGDLSVEGKF--NANQDEELMRAYFGGEARPAERGRVVIYKAMCDLLWTLWGLIQLAN-----------

General information: TITO was launched using: RESULT: Template: 3DXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1027 12678 12.34 57.11 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 12.34 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.356

(partial model without unconserved sides chains): PDB file : Tito_3DXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxq-query.scw PDB file : Tito_Scwrl_3DXQ.pdb: