Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------------------------------------------AGISNTNPPGGAPRPRQQCFLSADLGPDVMGQPTLLEATPFVNDMFDFHGYRCQMGKDCSHVR--CRGFPAAFKMTAR---------------------------------------------- 1D1Q Chain:A ((3-161)) IEKPKISVAFIALGNFCRSPMAEAIFKHEVEKANLENRFNKIDSFGTSNYH-VGESPDHRTVSIC-KQHGVKINHK-----GKQIKTKHFDEYDYIIGM--DESNINNLKKIQPEGSKAKVCLFGDWNTNDGTVQTIIEDPWYGDIQDFEYNFKQITYFSKQFLKKEL

General information: TITO was launched using: RESULT: Template: 1D1Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 203 5629 27.73 84.01 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : 27.73 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.108

(partial model without unconserved sides chains): PDB file : Tito_1D1Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1d1q-query.scw PDB file : Tito_Scwrl_1D1Q.pdb: