Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRRTTIDEAIARVDDWKGKEISYKPVSGGITNPNFKVDVE--GEHFFLKIPGAGT-DYINREVCHEANMIADESKAGPRVYYYFEDTGVEIFQWLDGYRQVTFGDVYDKDIFQSIFERIRDFHHLETKPLNL-------------KQSIFEQAWDMNARAKKGGY-ISP-------F-NDKMEYL---LSAIEKAL-AGSEELCPCHNDFWTNNLMYNEETNDLKIIDYEYASMNDPYVDLGLISAVNY---------FTEDMDVEMMKIYGGGKVD---ERAFARMKLNKIACDIKWAYWALYQAASSNVEFDYMNWYGQKMARLQHFWLDSRLDYWLDVAREKSTRIS 2QG7 Chain:D ((110-453)) -------------------SLEFQIINGG-TNILIKVKDMSKQAKYLIRLYGPKTD---NREREKKISCILYNKNIAKKIYVFFTN--GRIEEFMDG-YALSREDIKNPKFQKLIAKNLKLLHDIKLNENLYKELQVTQKVPGTRPSFLWNTIWKYFHLLNEERKKICSFDAKANILKLIDFDVLRDSIVEVESLCKRENSPIVLCHCDLLSSNIINTVG-DSISFIDFEYSCPMERAYDIANHFNEYAGFNCDWDLTPSKEEEYHFIMHYLGTDDEELINQLIREIQPFYICSHINWGLWSLLQGMHSS-DFDFINYGMTRLTASCLPI--------------------

General information: TITO was launched using: RESULT: Template: 2QG7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 1044 5475 5.24 20.98 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain D : 0.69 3D Compatibility (PKB) : 5.24 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.374

(partial model without unconserved sides chains): PDB file : Tito_2QG7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2qg7-query.scw PDB file : Tito_Scwrl_2QG7.pdb: