Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence GSAWFPGDPTYDCGISIFRPPKPGSRSRNGALAEVIYVNRGETF----KIIEGRYTCSIEQNCERPDCNLPRTWNYRGQ 3J70 Chain:U ((259-302)) -------------------------LLLNGSLAEEEVVIRSVNFTDNAKTIIVQLNTSVEINCTRPNNN----------

General information: TITO was launched using: RESULT: Template: 3J70.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain U - contact count / total energy / energy per contact / energy per residue : 65 -1359 -20.91 -33.98 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain U : 0.61 3D Compatibility (PKB) : -20.91 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.110

(partial model without unconserved sides chains): PDB file : Tito_3J70.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3j70-query.scw PDB file : Tito_Scwrl_3J70.pdb: