Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRTVAAPAPALAEVACFSRDLCKELVKEWSSLDSSCFSISTVSGGITNMLLKVSVKEGSDSESSVTVRLYGPNTDLVIDRERELQGSGLGYLEYLRMEWFRHSSMLGHYHLQVYTQRLLFCTHRCMETGEPAINASANNMKEPRIAAEIAKQLQKFHQVD--------------IPGSKEPQLWNDIFKFL-----KKASVLKFEDNEKQKRYETISFREIQDEVKELKDLSDLLHAPVVFAHNDLLSGNLM----LNDLEEKLYFIDFEYGSYSYRGFDIANHFNEYAGFECDYNLYPDKDVQYHFFRNYLSDRPSELKNRLFASICEKRNVGYLAFVQYKVQEQDLDDLYTETNTFRLASHLYWALWALIQARVSPIDFDYLGYFFLRRHVVPNRKLYNL 2QG7 Chain:A ((100-445)) ----------------------KDLVNP-NEVDSLEFQI--ING--TNILIKV---KDMSKQAKYLIRLYGP-TDEIINREREKKISCI------------------LYNKNIAKKIYVFFTNGRIEEFMDGYALSREDIKNPKFQKLIAKNLKLLHDIKLNENLYKELQVTQKVPGTRPSFLWNTIWKYFHLLNEERKKICSFD--AKANILKLIDFDVLRDSIVEVESLCKRENSPIVLCHCDLLSSNIINTVG---EGDSISFIDFEYSCPMERAYDIANHFNEYAGFNCDWDLTPSKEEEYHFIMHYLGTDDEELINQLIR----------------------------EIQPFYICSHINWGLWSLLQGMHS---FDFINYGMTR------------

General information: TITO was launched using: RESULT: Template: 2QG7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1186 -49473 -41.71 -175.44 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -41.71 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.296

(partial model without unconserved sides chains): PDB file : Tito_2QG7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2qg7-query.scw PDB file : Tito_Scwrl_2QG7.pdb: