Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MWQAISRLLSEQVGEGEIELRNELPGGEVHAA--------WHLRYA----GHDFFVKC--DEREMLRG-FTAEADQLELLSRSKTVVVPKVWAVGSDRDYSFLVMDYLSPRPLDAHNAFILGQQLARLHQWSDQPQFGLDFDNALSTTPQPNTWQRRWSTFFAEQRIGWQLELAAEKG-ITFGNIDAIVEHVQQ---RLASHQPQPSLLHGDLWSANCALGPDGPYIFDPACYWGDRECDLAMLPL----HTDQPPQIYDGYQSVSPLPLDFLDRQPIYQLYTLLNRARLFGGQHLATAQKAMDRLLAV 3F7W Chain:A ((10-277)) ---------------------TELTGREVAAVAERGHSHRWHLYRVELADGTPLFVKALPDDAPALDGLFRAEALGLDWLGRSFGSPVPQV----AGWDDRTLAMEWVDERPPTPEAAERFGHQLAAMHL-AGAESFGATWDGYIGPLPMDNTPRSTWPEFYAEQRILPYLRRAADRGALTPGDVR-LVEKVLDALDHLAGDPEPPARIHGDLWNGNVLWQDDGAVVIDPAAHGGHREADLAMLALFGLPYLD---RVRDAYNEVAPLAEGWRARIPLHQLHPLLVHVCLFGAAYRTT-----------

General information: TITO was launched using: RESULT: Template: 3F7W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1205 -16854 -13.99 -68.79 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -13.99 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.326

(partial model without unconserved sides chains): PDB file : Tito_3F7W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3f7w-query.scw PDB file : Tito_Scwrl_3F7W.pdb: