Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDIISRKYINEGFNSKAYIINDDYILLDGVNQNSYKNYQKYVNVINQISNVKSLEIPRIIELIEPCEEYPNGALIYKMIKGHTFRKEHIEIVN---LDNIAKKLAEFMDELYEIRVDFDKDEYI-----KNELEITEQSV-IELKEYLSESNYEKILSWFNEYKNYLL-TFNDYHFIHGDLWYENYILNDNNE---LVGIVDFEGSGMGDPAYD-IAALYYLGTGFINKVLSYYKYTDEDL-IKRVSMLIKAREIADFDDMVKNYPEEVEEQVDKIKKVL 3TDV Chain:A ((19-272)) ISIQSVESLGEGFRNYAILVNGDWVFRFPKSQQGADELNKEIQLLPLLVGCVKVNIPQYVYIGKRSDGNP--FVGYRKVQGQILGEDGMAVFPDDAKDRLALQLAEFMNELSAFPVETAISAGVPVTNLKNKILLLSEAVEDQVFPLLDESLRDYLTLRFQSYMTHPVYTRYTPRLIHGDLSPDHFLTNLNSRQTPLTGIIDFGDAAISDPDYDYVYLLEDCGELFTRQVMAYRGEVDLDTHIRKVSLFVTFDQVS------------------------

General information: TITO was launched using: RESULT: Template: 3TDV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1012 -14208 -14.04 -59.45 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -14.04 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.429

(partial model without unconserved sides chains): PDB file : Tito_3TDV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3tdv-query.scw PDB file : Tito_Scwrl_3TDV.pdb: