Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGPVNTVRMREGEVGIDAPLVGRLIARQFPGWAALPVRRVDSSGTENAMFRLGTGLVVRLPRHPGAVADVTHEQRW-LPRLGPLLPVATPEPAGLGAPDEDFPWPWSVYRWLDGRNPVAGAV-----AEPECLAERLGSFVAALRRIDPHDGPPASRGAPLATRD---EPTRAALARLTGLTGLTDRIDTAAVTALWEEALR-APAHCGPPAWAHGDLSPGNVLVDGDGLGAVIDFGCAGVGDPAVDLIVAWNLLPASARDTFREAVGADDAEWARGRGWALSISLIQLPYYRHTNPALAENSRHVIAEILAEAGRR 3HAV Chain:A ((2-258)) -------------VNLDAEIYEHL-----NKQIKINELRYLSSGDDSDTFLCNEQYVVKVPKRDSV--RISQKREFELYRFLENCKLSYQIPAVVYQSD-----RFNIMKYIKGERITYEQYHKLSEKEKDALAYDEATFLKELHSIEIDCSVSLFSDALVNKKDKFLQDKKLLISILEKEQLLTDEM-LEHIETIYENILNNAVLFKYTPCLVHNDFSANNMIFRNNRLFGVIDFGDFNVGDPDNDFLC---LLDCSTDDFGKEF----------GRKV--------LKYYQHKAPEVAE----------------

General information: TITO was launched using: RESULT: Template: 3HAV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 971 16069 16.55 65.85 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : 16.55 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.306

(partial model without unconserved sides chains): PDB file : Tito_3HAV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3hav-query.scw PDB file : Tito_Scwrl_3HAV.pdb: