Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNRRHSAPLALLQRATSFYDEQRKSNRDKEYPMDSLKQLLQEQYQLQAQTISPQKGG--WAALAYRVETKKHTYFLKMYEKSRTSTPKWTALIDEYVPALIWLNEQNDLNGKVPVPILTKNGQCKCENDKGIFLLYEHIEGETIGPQQLTNDQVEQLATIIAALHAIGEETAPIATAQ-LKEDFSLPFAVSLYKLLTEQLATLPDDIQTTIAP---FSQ---PLLSLIESTEKRANTLKQRPLRYALCHTDLHHWNLMTSQGE-LVLIDWEGLKLAPVEADMMFV---VDECYNNAF-MDHYRKRHLDYVIDQECLAFYQGRRKLEDIWEFLEQLLFDEQKPTERAAILEGLEKELEAVAKACL 3I1A Chain:A ((11-306)) -----------------------------------LIELLKVHYGIDIHTAQFIQGGADTNAFAYQADSESKSYFIKL---------KY-GYHDEINLSIIRLLHDSGIK-EIIFPIHTLEAKLFQQLKHFKIIAYPFIHAPNGFTQNLTGKQWKQLGKVLRQIH---ETSVPISIQQQLRKEIYSPKWREIVRSFYNQIEFDNSDDKLTAAFKSFFNQNSAAIHRLVDTSEKLSKKIQPDLDKYVLCHSDIHAGNVLVGNEESIYIIDWDEPMLAPKERDLMFIGGGVGNVWNKPHEIQYFYEGYGEINVDKTILSYYRHERIVEDIAVYGQDLLSRNQNNQSR-------------------

General information: TITO was launched using: RESULT: Template: 3I1A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1228 -7568 -6.16 -26.84 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -6.16 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.301

(partial model without unconserved sides chains): PDB file : Tito_3I1A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3i1a-query.scw PDB file : Tito_Scwrl_3I1A.pdb: