Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVELTDPDLERLRRRLAPAHIEDLRPLTGGASSLTYAGQRLGDRVVVKMAPPG----IQPTRNRDVLRQCRIIKAL-RATPVPVPDVLWADAGDPPEIPPLFVMSWIDGSSLEPLFDLDCACE-SEDIVAERFR----SAAATMAQLHRIQPAAIGLGSEPIVGAEAEID-----RWCRA--------------LETVDPTLAAGWIDLGKALRAAAPPPLPPAVVHGDFRLGNLRAVDGRITGVLDWEIWSVGDPRVDVGWFLINCDRQTYQRATPYAGATPSPA-----ELVSIYCAAAGYRLPDLAWFQALACFKSAATWSLIVKHN--RRRH-----RPDANVEAM---AQVLPHLLSRACILLD 3ATT Chain:A ((48-355)) -------------------------------------GRSIQQKLVARVAPAAEDVPVFPTYRLD--HQFEVIRLVGELTDVPVPRVRWIETTGDVLGTPFFLMDYVEGVVPPDVMPYTFGDNWFADAPAERQRQLQDATVAALATLHSI-PNAQNTFSFLT-----DTTLHRHFNWVRSWYDFAVEGIGRSPLLERTFEWLQSHWPDDAAARE--------PVLLWGDARVGNVLYRDFQPVAVLDWEMVALGPRELDVAWMIFA--HRVFQELAGLATLPGLPEVMREDDVRATYQALTGVELGDLHWFYVY----SGVMWACVFMRTGARRVHFGEIEKPD-DVESLFYHAGLMKHLLGE------

General information: TITO was launched using: RESULT: Template: 3ATT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1170 -34341 -29.35 -132.59 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -29.35 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.347

(partial model without unconserved sides chains): PDB file : Tito_3ATT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3att-query.scw PDB file : Tito_Scwrl_3ATT.pdb: