Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------------------AGISNTNPPGGAPRPRQQCFLSA-DLGPDVMGQPTLLEATPFVNDMFDFHG--YRCQMGKDCSHVRCRGFPAAFKMTAR---------------------------- 1HL6 Chain:A ((10-152)) AEEFEVDEDGDQGIVRLKEKAKHRKGRGFGPGPQRSVEGWILFVTSIHEEA----Q--EDE--IQEKFCDYGEIKNIHLNLDRRTGFSKGY-ALVEYETHKQALAAKEALNGAEIMGQTIQVDWCFVK

General information: TITO was launched using: RESULT: Template: 1HL6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 51 1782 34.94 26.60 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : 34.94 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.243

(partial model without unconserved sides chains): PDB file : Tito_1HL6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1hl6-query.scw PDB file : Tito_Scwrl_1HL6.pdb: