Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNLEQDIRAILRTEIKKHLKFKDVQCELNEIRSKNGVYVYRIITTSTSYVIKYFEKNE----F---RRELDYYNLLIELEIPTIPVISMTDQSIILED---IEQSETYRLGFESD--LENENVARGLVAWYTQFHKKGRIYLKQNPEQKAS-LYNEYNELTKNVITDIMTK----TGTNHYKYWHILINHFDDLIAQ-----SKSYTSTLTYNDFYYTNFIVSKD--ESEVIMFDYNFLGVGYRYSDVRNIVSSLKG----------------NAKSLFLACYP-----QCNEGEVILDDVLADLFVLKEAYKRDQFPSWAKIPVEQLDNGVFEQKVLKLKHYFKFD 4OCV Chain:A ((31-310)) --------------VASHFALEGTVDSIEPYGDGHINTTYLVTTDGPRYILQRMNTGIFPDTVNLMRNVELVTSTLKAQGKETLDIVRTTSGDTWAEIDGGAWRVYKFIEHTMSYNLVPNPDVFREAGRAFGDFQNFLSGFDANQLTETIAHFHDTPHRFE-DFKKALAADELGRAAGCG-PEIEFYLSHADQYAVVMDGLRDGSIPLRVTHNDTKLNNILMDATTGK-ARAIIDLDTIMPGSMLFDFGDSIRFGASTALEDERDLDKVHFSTELFRAYTEGFVGELRDSITAREAE--------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4OCV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 962 -25807 -26.83 -109.81 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -26.83 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.254

(partial model without unconserved sides chains): PDB file : Tito_4OCV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ocv-query.scw PDB file : Tito_Scwrl_4OCV.pdb: