Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFLTEANVLDYLTGRGFAGP--E--F-VVRGEWTVRNLSRRNRNFRVTRGGREFLVKQAGTW-DL------PGRASIEREADLCRRAATDPCFGALRPLVPDVYSYDPDHSILIFEFLPD-EASLSDVPERL--DARTARLAGELMADYHRQMQSAAL-A-------EHFPGSLPGYFSMHR--WD----SERLVTRSQGQR-ELVRLVKRHAAFAPALESAAAE--WRPGALIHGDWKLENCLISNDGARMHVVDWELAGWGDARWDVATLLQSWWKRWVRDPAE------------YRLEAMRPELRALLNPS-----E-----------------------------DEVAAILRFAAVRMLQSAWES--LQDIPAIHGE------AVRMAQVSLNILTNPEWAGEAVFGHD 2PYW Chain:A ((8-407)) -PLNEKSLVDYIKSTPALSSKIGADKSDDDLVIKEVGDGNLNFVFIVVGSSGSLVIKQALPYIRCIGESWPMTKERAYFEATTLRKHGNLS-----PDHVPEVYHFDRTMALIGMRYLEPPHIILRKGLIAGIEYPFLADHMSDYMAKTLFFTSLLYHDTTEHRRAVTEFCGNVELCRLTEQVVFSDPYRVSTFNRWTSPYLDDDAKAVREDSALKLEIAELKSMFCERAQALIHGDLHTGSVMVTQ--DSTQVIDPEFSFYGPMGFDIGAYLGNLILAFFAQDGHATQENDRKEYKQWILRTIEQTWNLFNKRFIALWDQNKDGPGEAYLADIYNNTEVLKFVQENYMRNLLHDSLGFGAAKMIRRIVGVAHVEDFESIEEDKRRAICERSALEFAKMLLKERRKFK-------

General information: TITO was launched using: RESULT: Template: 2PYW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1441 -8117 -5.63 -25.85 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -5.63 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.400

(partial model without unconserved sides chains): PDB file : Tito_2PYW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2pyw-query.scw PDB file : Tito_Scwrl_2PYW.pdb: