Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MWQAISHLLSEQLGEGEIELRNELPGGEIHAAWHLRYAGRDLFVKCDERELLPIFTAEADQLELLSRSKTVTVPQVWAVGSDRDYSFLVMEFLPAR-PLDA-------HNAFILGQQLARLHQWSDQPQFGLDFDNDLSTTPQPNAWQRRWSTFFAEQRIGWQLELAAEKGLEFGNIDAIVEHIQQRLASHQPQPSLLHGDLWSDNCALGPDGPYIFDP-ACYWGDRECDLAMLPL----HPEQPPQIYDGYQSVLPLPQGFLERQPVYQLYTLMNRAILFGGEHLVNAQRALERVLAA 3DXQ Chain:B ((4-254)) --DEARAKLAAIPMLAGYTGPLERLGGLTNLVFRA----GDLCLRIP------NRANEAVAAREAAKA-GVS-PEVLHVDP--ATGVMVTRYIAGAQTMSPEKFKTRPGSPARAGEAFRKLHGSGAVFPFRFELF----------AMIDDYLKVLSTK-----NVTLP---AGYHDVVREAGGVRSALAAHPLPLAACHCDPLCENFLDTGERMWIVDWEYSGMNDPLWDLGDLSVEGKFNANQDEELMRAYFGGEAR-PAERGRVVIYKAMCDLLWT---------------------

General information: TITO was launched using: RESULT: Template: 3DXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1023 -36536 -35.71 -158.85 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain B : 0.67 3D Compatibility (PKB) : -35.71 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.248

(partial model without unconserved sides chains): PDB file : Tito_3DXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxq-query.scw PDB file : Tito_Scwrl_3DXQ.pdb: