Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSQVDTLDTQKLAEY-LEQHIDGFKGPIEADKFEGGQSNPTFKITAASGAYV-LRRQPPGKLLKSAHAVDREFRV-MAALKDTDVPVPN-VLHLCEDRDVIGSMFYV-MEFCEGRILWSAGLPE-MGEGEAANAVRGEMYSEMN-RVLAAM-HSVDLEAVGLTDYGKPGNYFERQLGRWTQQYEASKLQEIPAMD-SLI-EWLQANQPEDD-GQVSLVHGDYRLDNM-MWHPEKPQVIAVLDWELSTLGHP-LADLAYQC-MGMRMPQRGAKMAGLQGKDRTALGIPTEKEYVAMYCERRGISQIDNWEFYLAFS-FFRLAAICQGVA-KRAEDGNASNKQAAEVGALVEP-LA-TMAMQIINEGA 3DXP Chain:A ((20-359)) -----RFDTEALEAWMR-QHVEGFAGPLSVEQF-KGQSNPTFKLVTPGQTYVMRAK---------PGAIEREYRVMDA-LAGTDVPVAKMY-ALCEDESVIGRAFYIMEFV-SGRVLWDQSLPGMSPAERTAIYD--------EMNRVIAAMHTVDYQAIGLGDYGKPGNYFQRQIERWTKQYKLSETESIP--AMDSLMDWLPQHIPQEDADLTSIVHGDYRLDNLMF-HPTEPRVLAVLDWELSTLGHPMG-DFGYHCMSWHIAPGQFR---GIAGLDHAALGIPDEASYRKLYEQRTGRPITGDWNFYLAFSMF-RIAGILQGI-MKRVVDGTASSAQALDAGKRARPMAEMGWEYAKKAKQ-

General information: TITO was launched using: RESULT: Template: 3DXP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1401 19178 13.69 61.67 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : 13.69 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.465

(partial model without unconserved sides chains): PDB file : Tito_3DXP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxp-query.scw PDB file : Tito_Scwrl_3DXP.pdb: