Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------------------------------------------------------------------GECHITIWEGNTPIGTEIAIEGREYVTIAGYQCNAGAGCT--AHCIGLPKNLKERGVYH--------------------------------------------------------- 1OCX Chain:A ((1-182)) STEKEKMIAGELYRSADETLSRDRLRARQLIHRYNHSLAEEHTLRQQILADLFGQVTEAYIEPTFRCDYGYNIFLGNNFF-ANFDCVMLDVCPIRI-GDNCMLAPGVHIYTATHPIDPVARNSGAELGKPVTIGNNVWIGGRAVINPGVTIGDNVVVASGAVVTKDVPDNVVVGGNPARIIKKL

General information: TITO was launched using: RESULT: Template: 1OCX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 100 -12624 -126.24 -229.52 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.54 3D Compatibility (PKB) : -126.24 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.54 QMean score : 0.216

(partial model without unconserved sides chains): PDB file : Tito_1OCX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ocx-query.scw PDB file : Tito_Scwrl_1OCX.pdb: