Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAAVRVLVASRLAAASAFTSLSPGGRTPSQRAALHLSVPRPAARVALVLSGCGVY-------DGTEIHEASAILVHLSRGGAEVQIFAPDVPQMHVIDHTKGQPS-EGESRNVLTE-SARI-ARGKITDLANLSAANHDAAIFPGGFGAAKNLSTFAVDGKDCKVNKEVERVLKEFHQAGKPIGLCCIAPVLA--A-------KVLRGVEVTVGHEQEEG---------GKWPYAGTAEAIKALGAKHCVK-EVVEAHVDQKNKVVTTPAFMCETALHYIHDGIGAMVRKVLELTGK 1QVV Chain:B ((2-236)) ----------------------------------------APKKVLLALTSYNDVFYSDGAKTGVFVVEALHPFNTFRKEGFEVDFVSETGKFGWDEHSLAKDFLNGQDETDFKNKDSDFNKTLAKIKTPKEVNADDYQIFFASAGHGTLFDY----------PKAKDLQDIASEIYANGGVVAAVCHGPAIFDGLTDKKTGRPLIEGKSITGFTDVGETILGVDSILKAKNLATV-EDVAKKYGAKYLAPVGPWDDYSITDGRLVTGVNPA----------SAHSTAVRSIDALK-

General information: TITO was launched using: RESULT: Template: 1QVV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1121 3482 3.11 16.90 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain B : 0.62 3D Compatibility (PKB) : 3.11 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.318

(partial model without unconserved sides chains): PDB file : Tito_1QVV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1qvv-query.scw PDB file : Tito_Scwrl_1QVV.pdb: