Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMDSQIQSLPEAIRKYIEGREYTIDDMGKSGSKVLIF----EDMVLKITDK-----PCDDKDAVEMMRWLEGKIPAPQVIVFEEDDSYSYLLMTKVRGKVACDKYYLER-PKELVPLLSKSIKMLQSIDITDCPVVKNVDRELKKAAYRVKNGLVDISDAEPDTFGENGRFRDPEELLSWLQENRPPYEPVLSHGDLCLPNILIEKGNISGFIDMGNCGIADKWEDIAILYRSLRHNF-DGTYGKIYPGLEPDSFFEELGIEPDREKIDYYILLDELF 1J7U Chain:B ((2-264)) ---AKMRISPE-LKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLKMTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEYEDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNN---DLADVDCENWEEDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKWYDIAFCVRSIREDIGEEQYVEL--------FFDLLGIKPDWEKIKYYILLDELF

General information: TITO was launched using: RESULT: Template: 1J7U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1135 58778 51.79 233.25 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain B : 0.83 3D Compatibility (PKB) : 51.79 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.570

(partial model without unconserved sides chains): PDB file : Tito_1J7U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1j7u-query.scw PDB file : Tito_Scwrl_1J7U.pdb: