Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTGAGAADATEDAATDATRGTDATRGTDATGGTDGPVPAARTAEEDRLVARVEELVG-GRVTAIERQ--PRWRKAWYLTVDRDGAELALYVRGDKQIDAEPYPGLDREAAILRILER-NGVPVPHVHGMSSDPIGIIMDRVPGTRDVAEAAD-------DAQRRGIAEQYMEILARMHSIDVAEFAAAGIEVPTTPEGAQLAFVDANERLYRRTKKAPEPLVEWALRWARRRLPTAGNRARFIHGDTG--QFLFVDGRITCVYDFEASHIGDPLSDLAGLRTRAGTEPLGADIEHMIRHYQRVAGTTIDPSALSFYTATYMLTAVMALSGPLTELRPADQQAEYLTWDLMVRRAMLWAIAEVEGVKIEPAPPVTLPTGYPARVTTVLEGTVRRMVPATGVDEANQSAALALAQWAGAMVAVGMANVERDLDRAAVLLGHRPADQAAADAELERFVLAAGPEHDLALLEYFAAQTEARVAEAVPMRTRLEQYALPKVVL 5UXD Chain:A ((5-255)) ------------------------------------------EDLDALLDLAARHGLDLDGGTLRTEEIGLDFRVAFARAH---DGGDWVLRLPRRPDV--LERAAVEGRLLAMLAPHLDVAVPDWRIST--SELIAYPLLPGSPGLTVAADGEVSWHVDMASTVYARSLGSVVAQLHAVDAEAAAATGIE-VRSPAQ-VRGAWRQDLARVGAEFEIAPALRERWEAWLADDGC-WPGHSVLTHGELYPAHTLVEDERITAVLDWTTAAVGDPAKDLMFHQVSA---PS-AIFEVALQAYAEGGGRP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5UXD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 959 10185 10.62 42.79 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : 10.62 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.218

(partial model without unconserved sides chains): PDB file : Tito_5UXD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5uxd-query.scw PDB file : Tito_Scwrl_5UXD.pdb: