Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVRIPDELNAQRRLGPDWENWLDRLPRLCDEIVSDWGLTVVG--EPTNGFASIVIPVSTSDGDAMLKVGFDSS---PETEHEHLALTYWAG-DGA--VTMFRAD------------PARHAMLLEQLHSRDLSQEW-DLQACEIVAGFYSRLHRPAPP--R---LRPLTGFVDRWLGALEA---DARE--M-PVPRRLIDHALNRGRAFVD---DPASVGRIIHGDLHYENVLAADR---EPWLVIDPQPM-SGDPHYELAPMLWNRWDEMDGYLRESIQRRFYTLVEAAGLD---DDRARDWVIVRMILNAHWAVEDAKRMNRALDADERDWITRCIAVAKAVQR 6EF6 Chain:A ((27-324)) ------------------------DVTIAQQALTHYDVSDNASLRLLNLSENATYLVEDGEHQSILRVHRQDYHQPHEIESELDWLAALRTDSDVTVPTVVPARDGRRVVTVDPADVPRHVVHFEMVGGAEPDEESLTLDDFQTLGRITASLHEHSQRWTRPAGFGRFSWDWEHCLGDTPRWGRWQDAEGVGASETALLTRAQDLLHRKLEEYGSGPDRYGLIHADLRLANLLVDSSTPQRTITVIDFDDCGFGWYFYDFGTAVSFIEHD--PRLGEWQESWVAGYRSRRELPAADEAMLPSFVFLRRLLLLAWMGSHTHS-------------------------

General information: TITO was launched using: RESULT: Template: 6EF6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1113 -12248 -11.00 -48.41 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -11.00 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.260

(partial model without unconserved sides chains): PDB file : Tito_6EF6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-6ef6-query.scw PDB file : Tito_Scwrl_6EF6.pdb: