Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFARDALSTA-VETACDPDPAVDTISTIEAGNNHTYRVTLADGTDLFLKVG-TRFPDAFPAEPAT-MRRVRAETDLPVPR-VHGTGTDPLEYPYAVYE-YVPDCEAEWAGDLSH-EAAERLCREAG-RHLCEL-HQITFPQFGRIGLDTDASADDTLVADAPDADALTVVDPTPFDDLLRQSLDRQVTELADSPFDTRRD-SLE-AFGTDLIDRSDFADVTPALVHGDYRLGNL-CVDPSAEQITAAVLDWELPTALDP-LWDAVMA-QSLLTAG----------HRLDPDSRQTLRRAFWEAYGTSTADTPRRRCYELLAR-IRLARHLDTE-CRGLSEAARRARITDHHEAFDA-LL-VDR------- 3DXP Chain:A ((20-359)) RFDTEALEAWMRQHVEGFAGPL-SVEQFKGQSNPTFKLVTPGQ-----TYVMRAKPGAIEREYRVMDAL--AGTDVPVAKMYALC-EDESVIGRAFYIMEFVSGRVLWDQSLPGMSPAERTAIYDEMNRVIAAMHTVDYQAIG-------------------------LGDYGKPGNYFQRQIERWTKQYKLSETESIPAMDSLMDWLPQHIPQED--ADLTSIVHGDYRLDNLMFHPTEPRVL--AVLDWELSTLGHPMGDFGYHCMSWHIAPGQFRGIAGLDHAALGIPDEASYRKLYEQRTGRPITGD---WNFYLAFSMFRIAGILQGIMKRVVDGTASSAQALDAGKRARPMAEMGWEYAKKAKQ

General information: TITO was launched using: RESULT: Template: 3DXP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1343 -3064 -2.28 -10.38 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -2.28 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.234

(partial model without unconserved sides chains): PDB file : Tito_3DXP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxp-query.scw PDB file : Tito_Scwrl_3DXP.pdb: