Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ----KQIAQLKEYLRNPPCKVTIYAPPLK-QGQTQLRTVMGFASAGKNEDVPVKIASTGHTYQC---RTDATCEEPVCHGLPNGWTYEGVY 1FX7 Chain:A ((145-230)) GADDANLVRLTELPAGSPVAVVVRQLTEHVQGDIDLITRLKDAGVVPNARVTVETTPGGGVTIVIPGHENVTLPHEMAHAV----KVEKV-

General information: TITO was launched using: RESULT: Template: 1FX7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 267 13931 52.17 178.60 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : 52.17 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.407

(partial model without unconserved sides chains): PDB file : Tito_1FX7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1fx7-query.scw PDB file : Tito_Scwrl_1FX7.pdb: