Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTRPPTPTADTVRRLVRTLLKDGAADASGPEVRPAAPGADPVTWLVG----GRHVLRLARDRDAAARQRRELRLRDLVRTHVPVAVPVSVAQGEWAPGLAYTLDTRVPGASGAEHD-----------VSAVGEADLAGLLTGLREVPARQAETLGVPRAAPRSLEALRAAAEPAAERLAGADEFDAARLRQLTRAAAVQLAAQSAPPVLVHHALTGGHLVVSADGRVRAVLGWAGTVLGDPAEDIAGLALAVGSPAAVRAATLAGYGARPCLRGLWLARCDAVLQLAARLDGTGTAPLPRLRTRLRHAWEAILLERVTELRAEAGEDGERRA 5UXD Chain:A ((3-250)) ----MPEDLDALLDLAARHGLD----LDGGTLRTEEIGLDFRVAFARAHDGGDWVLRLPRRPDVLERAAVEGRLLAMLAPHLDVAVPDWRIST-----SELIAYPLLPGSPGLTVAADGEVSWHVDMASTVYARSLGSVVAQLHAVDAEAAAATGIEVRS---PAQVRGAWRQDLARVGAEFEIAPALRERWEAW-LADDGCWPGHSVLTHGELYPAHTLVED-ERITAVLDWTTAAVGDPAKDLMFHQVSAPS--AIFEVALQAYAE----------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5UXD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 934 -12386 -13.26 -53.16 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -13.26 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.295

(partial model without unconserved sides chains): PDB file : Tito_5UXD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5uxd-query.scw PDB file : Tito_Scwrl_5UXD.pdb: