Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGVKTKLFYEDIKPFFDIKSLQETKNGESHTVYILDN---DYILKIYEEE--NLFNIDAEIELLNYTKK--LCVPKVIKDDIFIKGKRGLVFSKAKGE-SVVEFVKSTHLEQIGQFLNSFHKMTKNKKHDNLSAFGKSQLKVMIEKTC-NKAFKDEFDCLK-----IE--LKNDGIIHGDLFLDNATFCGDKLTCVFDFSDACEGDFIFDLAVVALSWCSNKEEINILLKAYDKEIKL---DDFIIYLRYASLYYCVKRHLTNRDYDNIIFKNKFIDLI 4R7B Chain:A ((40-275)) ------------------LSVEQL-GGMTNQNYLAKTTNKQYIVKFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFD----IEAGIKVNEYIESAITLDSTSIKTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLEKRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTSQEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWT--------------------

General information: TITO was launched using: RESULT: Template: 4R7B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 880 40291 45.79 185.67 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 45.79 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.305

(partial model without unconserved sides chains): PDB file : Tito_4R7B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4r7b-query.scw PDB file : Tito_Scwrl_4R7B.pdb: