Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence RLYDCRVA---IWQPPMDSRTTVETLAEATHFNLG-ESVRVLRG-----RFTCKAEQKCGNVICNLP-EGYKYQSI 1TOC Chain:R ((57-119)) --HSSEMHSSCLGDPPTSCAEG----TDITYYDSDSKTCKVLAASCPSGENTFESEVEC-QVACGAPIEG------

General information: TITO was launched using: RESULT: Template: 1TOC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain R - contact count / total energy / energy per contact / energy per residue : 181 11190 61.82 211.13 target 2D structure prediction score : 0.36 Monomeric hydrophicity matching model chain R : 0.67 3D Compatibility (PKB) : 61.82 2D Compatibility (Sec. Struct. Predict.) : 0.36 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.220

(partial model without unconserved sides chains): PDB file : Tito_1TOC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1toc-query.scw PDB file : Tito_Scwrl_1TOC.pdb: