Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence YKCRISLMNGSDSTDDYADGKPGDTVNLEANNGDIVKVYIR--DNCYYDILNKEK--MPASYT--IKT 1W6X Chain:A ((173-228)) MRAEA--------LFDFTGNSKLE---LNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILK-

General information: TITO was launched using: RESULT: Template: 1W6X.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 185 -11032 -59.63 -220.63 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -59.63 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.277

(partial model without unconserved sides chains): PDB file : Tito_1W6X.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1w6x-query.scw PDB file : Tito_Scwrl_1W6X.pdb: