Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQRQTELKNWLQTVYPERDFDLSFAAADADFRRYFRAAFSDGGSVVC-MDAPPDKMSVAPYLKVQKLFDM--VNVPQVLHADTDLGFVVLNDLGNTTFLTAMLQEQGEAAHK-ALLLEAIGELVGLQKASREGVLPEYDRETMLR-EINLFPEWFVAKELGRELTFKQRQLWQQTADTLLPPLLAQPK-VYVHRDFIVRNLMLT-----RGRPGVLDFQDALYGPISYDLVSLLRDAFIEWEEEFVLD-LVIRYWEKARAAGLPVPAEFDEFYRRFEWMGVQRHLKVAGIFARLYYRDGKDKYRPEIPRFLNYLRRVSRRYAELAPLYALLVELVGDEELETGFTF-- 3CSV Chain:A ((4-333)) -SREDEIRDFLAT---------HGYADWNRTPRYQRLRSPTGAKAVLMDWSPEEGGDTQPFVDLAQYLRNLDISAPEIYAEEHARGLLLIEDLGDALFTEVINND---PAQEMPLYRAAVDLLIHLHDAQTPE-LARLDPETLSEMTRLAFSEYRYAILG--DAAEDNRKRFEHRFAQILSAQ-LEGDMVFVHRDFHAQNLLWLPEREGLARVGVIDFQDAKLGHRAYDLVSLLQDARRDVPAQVEAQMI--DHYIQAT------GVDESHFRSAYAVIAVQRNMRILGIFARLSQRFGKRHYIEFVPRVWAHFERGLA-HPALASAAEEILNALPAPAPEVLERLRA

General information: TITO was launched using: RESULT: Template: 3CSV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1459 -3757 -2.57 -12.20 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -2.57 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.385

(partial model without unconserved sides chains): PDB file : Tito_3CSV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3csv-query.scw PDB file : Tito_Scwrl_3CSV.pdb: