Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTNKMKNHKITKLGGLNNSNYLLECE--NNKYVLRIPSKDNKNNFSEENFVLIFANLNKLSPPIIYHNKDNGILISKFLEDSKVNMSTFTSLEFLEKLSINLRKLHILKCEH----IF------------NPFEHIRKNFHILKSKNFN---------------FHQDIDLVLNKLNILEEKLSKNMTIGLCHNDLNSSNVLYYN-KNVLFIDFEFSAMCDIFFDLATVSW-M--L--------DEKKRYFLIKSYFGYYSY----ELMEKLENYLFVVKLWNASWSFLKSLNT--NSTYDYKLGGNMIIDDLLSTL 2QG7 Chain:D ((110-450)) -----SLEFQIINGG-TNILIKVKDMSKQAKYLIRLYGPKTD-NREREKKISCILYNKNIAKKIYVFFT--NGRIEEFMDGYALSREDIKNPKFQKLIAKNLKLLHDIKLNENLYKELQVTQKVPGTRPSFLWNTIWKYFHLLNEERKKICSFDAKANILKLIDFDVLRDSIVEVESLCKR---ENSPIVLCHCDLLSSNIINTVGDSISFIDFEYSCPMERAYDIANHFNEYAGFNCDWDLTPSKEEEYHFIMHYLGTDDEELINQLIREIQPFYICSHINWGLWSLLQGMHSSDFDFINYGMTRLTASC------

General information: TITO was launched using: RESULT: Template: 2QG7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 962 3006 3.12 12.12 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain D : 0.66 3D Compatibility (PKB) : 3.12 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.387

(partial model without unconserved sides chains): PDB file : Tito_2QG7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2qg7-query.scw PDB file : Tito_Scwrl_2QG7.pdb: