Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTIQQEIFSILGIKGPVLLGEGSESQTYDYTADKVVKI-YKGPVEQDNLDHLCSIYTWLSTHHLPFAVPEIYAIESHEGTVYLIEKKLAGRPISAVYAQLQMYERQ-RLLSNYLEAVRHLQGVVLPTQPYGSIFHAPGPSPVPYQSWRKFLRE-TAPLKLPQTQDDLRQEGIDVARLLEKFFQDIENAPDTPEK-NFVHGDYFFGNVLVDDELEISAVLDVSWW--SVVGDHLMDIAGAVMFLDLYEYVTPQEIASL-TQQALALYGP---EILTAIRIYGVY-----YSLLLSDCKLLDPAAYSWSIKRLREYMQ-------------------------------- 3CSV Chain:A ((4-333)) -SREDEIRDFLATHGYADWNRTPRYQRLRSPTGAKAVLMDWSPEEGGDTQPFVDLAQYLRNLDI--SAPEIYAEEHARG--LLLIEDLGDALFTEVINN--DPAQEMPLYRAAVDLLIHLHD-------------AQTPELARLD--PETLSEMTRLAFSEYRYAILGDAAEDNRKRFEHRFAQILSAQLEG-DMVFVHRDFHAQNLLWLPEREGLARVGVIDFQDAKLGHRAYDLVSLLQ--DARRDV-PAQVEAQMIDHYIQATGVDESHFRSAYAVIAVQRNMRILGIFARLSQRFGKRHYIEFVPRVWAHFERGLAHPALASAAEEILNALPAPAPEVLERLRA

General information: TITO was launched using: RESULT: Template: 3CSV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1246 -5858 -4.70 -21.30 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -4.70 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.272

(partial model without unconserved sides chains): PDB file : Tito_3CSV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3csv-query.scw PDB file : Tito_Scwrl_3CSV.pdb: