Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGPVNTVRMREGEVGIDAPLVGRLIARQFPGWAALPVRRVDSSGTENAMFRLGTGLVVRLPRHPGAVADVTHEQRWLPRLGPLLPVATPEPAGLGAPDEDFPWPWSVYRWLDGRNPVAGAV-----AEPECLAERLGSFVAALRRIDPHDGPPASRGAPLATRD---EPTRAALARLTGLTGLTDRIDTAAVTALWEEAL-RAPAHCGPPAWAHGDLSPGNVLVDGDGLGAVIDFGCAGVGDPAVDLIVAWNLLPASARDTFREAVGADDAEWARGRGWALSISLIQLPYYRHTNPALAENSRHVIAEILAEAGRR 3UZR Chain:A ((22-276)) ------------MVNLDAEIYEHL-----NKQIKINELRYLSSGDDSDTFLCNEQYVVKVPKRDSVRISQKRELE-LYRFLENCKLSYQIPAVVYQSD-----RFNIMKYIKGERITYEQYHKLSEKEKDALAYDEATFLKELHSIEIDCSVSLFSDALVNKKDKFLQDKKLLISILEKEQLLTDEM-LEHIETIYENILSNAVLFKYTPCLVHNDFSANNMIFRNNRLFGVIDFGDFNVGDPDNDFLC---LLDCSTDDF--------------GKEFGRKV----LKYYQHKAPEVAE----------------

General information: TITO was launched using: RESULT: Template: 3UZR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 994 -22116 -22.25 -89.90 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -22.25 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.236

(partial model without unconserved sides chains): PDB file : Tito_3UZR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3uzr-query.scw PDB file : Tito_Scwrl_3UZR.pdb: