Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence SVRNPKYGDHCELTVWIHYKGK--DIP-----LMRYYVEI---GGDLTFDEKDGAWKHCVIKTTKQACEATWTGGSKSEPCPPKNINVD 1UYX Chain:A ((39-96)) ---------------WLSYAGTPVNIPSSGSYLIEYRVASQNGGGSLTFEEAGGAPVHGTIAIPATGGWQTWT----------------

General information: TITO was launched using: RESULT: Template: 1UYX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 76 -2280 -30.00 -47.50 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -30.00 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.178

(partial model without unconserved sides chains): PDB file : Tito_1UYX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1uyx-query.scw PDB file : Tito_Scwrl_1UYX.pdb: