Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAQPLSTAADIAQQDAVRQLCEQLEFFQQHPPLEIRPLAAGQSNLNYYLRTARGEYVLRRYAR--------QL-GVCRQQEFRCQQAAAAKQIAATPLLLHNHQQLLISEFLPGG-EPLKLTDSRLSLLADTLGI-LH---NLRVQTPLLQPASYLRQLLAQGQQITLQPAANLFAALQRCAEQLAGMATDLV---LCHLDLHADNLLWNGNKIWLL-DFEYSQLCDNSFDLAAIMLHF------ELTAAQQQRLLRQYSAQRRYPDRHTAERLAATLPQRLQLAKCLYSGFCWLWYQATPALHHRAN--SWQQRLQQLLQSETTEPFR-- 2PPQ Chain:A ((5-320)) --TDIT-------EDELRNFLTQYDVG------SLTSYKGIAENSNFLLHTTKDPLILTLYEKKNDLPFFLGLMQHLAAKGLSCPLPLPRKD-GELLGELSGRPAALISF--LEGMWLRKPEAKHCREVGKALAAMHLASEGFEIKRPNALSVDGWKVLWDKSEERADEVEKGLREEIRPEIDYLAAHWPKDLPAGVIHADLFQDNVFFLGDELSGLIDFYFACNDLLAYDVSICLNAWCFEKDGAYNVTKGKALLEGYQSVRPLS---EAELEALPLLSRGSALRFFLTRLYDWLTTPAGALVVKKDPLEYLRKLRFHRTIANVAEYGLA

General information: TITO was launched using: RESULT: Template: 2PPQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1304 -35165 -26.97 -124.70 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -26.97 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.371

(partial model without unconserved sides chains): PDB file : Tito_2PPQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ppq-query.scw PDB file : Tito_Scwrl_2PPQ.pdb: