Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSAANPPRPSRSLQGKVAIVTGAGSRGETIGNGRAIALLLAEDGAKVVCVD--------------REEALAQRTAELVLAENEGASALAVAADVSSAEECARVVDAALRLFGRVDVLVNGVGVLGPPGTAVDVDAARWARGLEVNVTSMMLMAKYAVPAMRDNEPEAGVRGSIVNLGSVAGLRGGTPSLLYPTSKCAVVNMTRAMAAHHAKDGVRVNCVCPGMLYTPMVYDAEGGMSAEVREARRRRSL----LQTEG--NAWDCAGPVRFLAGGEARWITGTVLTVDAGATCALAVSMPDGE 3PGX Chain:A ((12-277)) -----------SLQGRVAFITGAAR-----GQGRSHAVRLAAEGADIIACDICAPVSASVTYAPASPEDLDE-TARLV--EDQGRKALTRVLDVRDDAALRELVADGMEQFGRLDVVVANAGVLSW-GRVWELTDEQWDTVIGVNLTGTWRTLRATVPAMI----EAGNGGSIVVVSSSAGLKATPGNGHYSASKHGLTALTNTLAIELGEYGIRVNSIHPYSVETPMI-EPEAMMEIFARHPSFVHSFPPMPVQPNGFMTADEVADVVAWLAGDGSGTLTGTQIPVDKGA------------

General information: TITO was launched using: RESULT: Template: 3PGX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1361 -35683 -26.22 -145.05 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -26.22 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.463

(partial model without unconserved sides chains): PDB file : Tito_3PGX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3pgx-query.scw PDB file : Tito_Scwrl_3PGX.pdb: