Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------------------------------------------------------------------------------------------------------------------------------------------------------IFKKPVPTSCKLALTNGNKREVDAKLLPPSGTTILSDTSGAGIFTAK------VNSKCEFTSVSPALPTGFNI--EGSV------------------------------------------------------------ 3E5Z Chain:A ((2-291)) TLRAARPEFLDLFPAGAEARRLADGFTWTEGPVYVPARSAVIFSDVRQNRTWAWSDDGQLSPEMHPSHHQNGHCLNKQGHLIACSHGLRRLERQREPGGEWESIADSFEGKKLNSPNDVCLAPDGSLWFSDPTYGIDKPEEGYGGEMELPGRWVFRLA--PDGTLSAPIRDRVKPNGLAFLPSGNLLVSDTGDNATHRYCLNARGETEYQGVHFTVEPGKTDGLRVDAGGLIWASAGDGVHVLTPDGDELGRVLTPQTTSNLCFGGPEGRTLYMTVSTEFWSIETNVRGLEH

General information: TITO was launched using: RESULT: Template: 3E5Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 187 -5813 -31.09 -84.25 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : -31.09 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.357

(partial model without unconserved sides chains): PDB file : Tito_3E5Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3e5z-query.scw PDB file : Tito_Scwrl_3E5Z.pdb: