Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVSDYVDDESSVRINRKMELIKVPDESAGNAMIGISYLTREDGKIIADRIKELCNESRYNNSFWEEALYIKDKMMVSAKTVSSKDVIEINTYEQLREIDENSDQLDTDAISVICEAFKINKNDIYNITVLKKGMTNRSFLFECKGKKYIMRIPGEGTDMLINRREEAEVYNVVNKEKICDNVIYINPDNGYKITEFIENSRVCD-PFNEDDVKRCMDKLRTFHNLKLKVNHEFNILGQMKFYESLWNEKSVYDDYELTKANVLSLKKYVEDNVSEKVLTHIDAVPDNFLFAG-DEIRLIDWEYAGMHDPHVDIAXXAGMQDPHVDIAMFAIYSLYDREQTDRLIDAYFTGNCDKKTRLKIYCYIAMCGLLWSNWCEYKRQLGVEFGEYSLRQYRYAKDFYRIFINESEQIKEELK 4R7B Chain:A ((23-304)) ----------------------------------------------------------------------------------------------------------KIIKEKISSLLSQE-EEVLSVEQL-GGMTNQNYLAKTTNKQYIVKFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSIKTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLEKRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMND-------------PMWDLAALFLESEFTSQEEETFLSHYESDQ-TPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRAVKGLASYG-----------

General information: TITO was launched using: RESULT: Template: 4R7B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1345 -45497 -33.83 -162.49 3D Compatibility (PKB) : -33.83 2D Compatibility (Sec. Struct. Predict.) : 1D Compatibility (Hydrophobicity) : QMean score : ?

(partial model without unconserved sides chains): PDB file : Tito_4R7B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4r7b-query.scw PDB file : Tito_Scwrl_4R7B.pdb: