Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WDSP----VTHREHR-------PAPSPPQRCKVEFGRANKPIGQAIEYWDRD-FIIQG------YTFHCYADCTLKGDYNFPRNQGYWVTS 1QR4 Chain:A ((1-87)) -DNPKDLEVSDPTETTLSLRWRRPVAKFDRYRLTYVSPSGKKNEMEIPVDSTSFILRGLDAGTEYTISLVAE---KGRHKSKPTTIKGSTV

General information: TITO was launched using: RESULT: Template: 1QR4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 246 16498 67.07 239.10 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 67.07 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.215

(partial model without unconserved sides chains): PDB file : Tito_1QR4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1qr4-query.scw PDB file : Tito_Scwrl_1QR4.pdb: