Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence QWCIVTVFYQGRS----TGETFPTAKKVGRKYEFPGEGKGYAPYKFVCD-DQCNCVSAGRPFLTGMRLEGQ 1IGQ Chain:A ((305-358)) KKAIVQVEHDERPARLILNRRPPAEGYAWLKYEDDGQ-------EFEANLADVKLVA-----LI----EG-

General information: TITO was launched using: RESULT: Template: 1IGQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 154 6099 39.60 124.46 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 39.60 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.267

(partial model without unconserved sides chains): PDB file : Tito_1IGQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1igq-query.scw PDB file : Tito_Scwrl_1IGQ.pdb: