Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence YKCRISLMNGSD--STDDYADGKPGDTVNLEANNGDIVKVYIRDNC--YYDILNKEKM----PASYTIKT- 1CSK Chain:A ((11-68)) ---------GTECIAKYNFHGTAEQD---LPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANY-VQKR

General information: TITO was launched using: RESULT: Template: 1CSK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 155 15070 97.22 307.54 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 97.22 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.347

(partial model without unconserved sides chains): PDB file : Tito_1CSK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1csk-query.scw PDB file : Tito_Scwrl_1CSK.pdb: