Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence AAVLPQLCKVEMFDKNARFVGMARGNWDKDFVIKGH--TIKCNTR-----CETKD-VVLPKNWSVKG------- 1ICF Chain:I ((1-65)) ---L-TKCQEEVSHIPAVHPGSFRPKCDEN----GNYLPLQCYGSIGYCWCVFPNGTEVP-NTRSRGHHNCSES

General information: TITO was launched using: RESULT: Template: 1ICF.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain I - contact count / total energy / energy per contact / energy per residue : 139 2399 17.26 47.97 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain I : 0.61 3D Compatibility (PKB) : 17.26 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.254

(partial model without unconserved sides chains): PDB file : Tito_1ICF.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1icf-query.scw PDB file : Tito_Scwrl_1ICF.pdb: